When the paths that we take in life become overshadoweed with obstacles, the best route to take is to be optimistic and thankful. The people who become successful use their struggles to become stronger, and surround themselves with others who see opportunities from each failure.
Know too, that when we focus on God instead of self, and tell our obstacles about God, instead of telling God about our obstacles, we see tiny bits of progress each day as if there is light at the end of the tunnel.
So when given a choice, take the path of being thankful.